Ontology highlight
ABSTRACT:
SUBMITTER: Czescik J
PROVIDER: S-EPMC7839518 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20201116 3
Similarly to enzymes, functionalized gold nanoparticles efficiently catalyze chemical reactions, hence the term nanozymes. Herein, we present our results showing how surface-passivated gold nanoparticles behave as synthetic nanonucleases, able to cleave pBR322 plasmid DNA with the highest efficiency reported so far for catalysts based on a single metal ion mechanism. Experimental and computational data indicate that we have been successful in creating a catalytic site precisely mimicking that su ...[more]