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ABSTRACT: Aims
This prospective study aimed to compare the clinical outcomes between the use of Erbium:YAG (Er:YAG) laser in a nonablative mode, to the use of the pharmacological treatment of oral tadalafil for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).Methods
The laser group received two sessions of Erbium:YAG laser, administered intraurethrally in a long, nonablative train of long pulses (SMOOTH™ mode), applied at the level of the male prostatic urethra. Tadalafil group received oral tadalafil at a dose of 5?mg/day, consecutively for 2 months. Effectiveness was assessed using the International Prostate Symptom Score (IPSS) questionnaire, VAS (visual analogue scale) pain score, and maximum urethral flow at follow-up visits up to 12 months after initiating treatment. Adverse effects were recorded after each treatment and follow-up sessions.Results
The results show a significant decrease in the IPSS score in both groups up to the 12-month follow-up. The increase in Q-max was evident up to 3-months follow-up in the tadalafil group and up to 6 months in the laser group. The decrease in the VAS pain score was also significant in both treatment groups, lasting up to 3 months in the tadalafil group and up to 6 months in the laser group.Conclusions
The nonablative Er:YAG SMOOTH™ laser seems to be a promising treatment for this widely occurring condition. More studies are needed to confirm its safety and efficacy.
SUBMITTER: Gaspar A
PROVIDER: S-EPMC7839688 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Gaspar Adrián A Silva Joaquín J Silva Gustavo G Anchelerguez Raúl R Prats Jorge J Sagaz Alejandro A Rovere Eduardo E Alastra Mauricio M Pino Juan J Jauregui Alejandro A Farrugia Marcos M Villaroel Fabricio F Guareschi Jonathan J Vega Maximiliano M Biasiori Emanuel E Moyano Emanuel E La Rosa Antonio A Hreljac Irena I Vižintin Zdenko Z
Neurourology and urodynamics 20201110 1
<h4>Aims</h4>This prospective study aimed to compare the clinical outcomes between the use of Erbium:YAG (Er:YAG) laser in a nonablative mode, to the use of the pharmacological treatment of oral tadalafil for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).<h4>Methods</h4>The laser group received two sessions of Erbium:YAG laser, administered intraurethrally in a long, nonablative train of long pulses (SMOOTH™ mode), applied at the level of the male prostatic urethra. ...[more]