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Born in winter or spring more susceptible to all-cause and cardiovascular disease death in rural areas of China: results from a 11.9-year follow-up study.


ABSTRACT: There has been no evidence on the effects of birth season and birth month on mortality in China. We aimed to explore the association between birth season, birth month and all-cause and cardiovascular disease (CVD) death. A population-based sample of 21,338 Chinese rural participants aged ?35 years at baseline was included in our analysis. Age and multivariable adjusted Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the relationship between astronomical birth season (autumn as the reference), birth month (November as the reference), and all-cause and CVD mortality. During a median follow-up period of 11.9 years, 2,207 people died from all-cause and 1,214 people were attributed to CVD death. In multivariable adjusted analyses, for all-cause death, spring and winter had HRs (95% CIs) of 1.134 (1.005-1.280) and 1.162 (1.038-1.301), respectively; January, March, May, and August had HRs (95% CIs) of 1.249 (1.027-1.518), 1.234 (1.008-1.512), 1.276 (1.037-1.571), and 1.232 (1.003-1.513), respectively. For CVD death, spring and winter with HRs (95% CIs) of mortality were 1.232 (1.048-1.449) and 1.174 (1.007-1.369), respectively; March with HR (95% CI) of mortality were 1.343 (1.030-1.750) (all P?

SUBMITTER: Gao Z 

PROVIDER: S-EPMC7839939 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Born in winter or spring more susceptible to all-cause and cardiovascular disease death in rural areas of China: results from a 11.9-year follow-up study.

Gao Zihui Z   Liu Sitong S   Dai Yue Y   Guo Rongrong R   Wang Yali Y   Sun Zhaoqing Z   Xing Liying L   Sun Yingxian Y   Zheng Liqiang L  

Journal of human hypertension 20210127 12


There has been no evidence on the effects of birth season and birth month on mortality in China. We aimed to explore the association between birth season, birth month and all-cause and cardiovascular disease (CVD) death. A population-based sample of 21,338 Chinese rural participants aged ≥35 years at baseline was included in our analysis. Age and multivariable adjusted Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the relatio  ...[more]

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