Ontology highlight
ABSTRACT:
SUBMITTER: Pardo-Seco J
PROVIDER: S-EPMC7840454 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Pardo-Seco Jacobo J Gómez-Carballa Alberto A Bello Xabier X Martinón-Torres Federico F Salas Antonio A
Zoological research 20210101 1
Analysis of SARS-CoV-2 genome variation using a minimal number of selected informative sites conforming a genetic barcode presents several drawbacks. We show that purely mathematical procedures for site selection should be supervised by known phylogeny (i) to ensure that solid tree branches are represented instead of mutational hotspots with poor phylogeographic proprieties, and (ii) to avoid phylogenetic redundancy. We propose a procedure that prevents information redundancy in site selection b ...[more]