Ontology highlight
ABSTRACT:
SUBMITTER: Wei YD
PROVIDER: S-EPMC7840460 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Wei Yu-Dong YD Du Xiao-Min XM Yang Dong-Hui DH Ma Fang-Lin FL Yu Xiu-Wei XW Zhang Meng-Fei MF Li Na N Peng Sha S Liao Ming-Zhi MZ Li Guang-Peng GP Bai Chun-Ling CL Liu Wei-Shuai WS Hua Jin-Lian JL
Zoological research 20210101 1
Double sex and mab-3-related transcription factor 1 (Dmrt1), which is expressed in goat male germline stem cells (mGSCs) and Sertoli cells, is one of the most conserved transcription factors involved in sex determination. In this study, we highlighted the role of Dmrt1 in balancing the innate immune response in goat mGSCs. Dmrt1 recruited promyelocytic leukemia zinc finger (Plzf), also known as zinc finger and BTB domain-containing protein 16 (Zbtb16), to repress the Toll-like receptor 4 (TLR4)- ...[more]