Ontology highlight
ABSTRACT:
SUBMITTER: Nitta T
PROVIDER: S-EPMC7840694 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Nitta Takeshi T Takayanagi Hiroshi H
Frontiers in immunology 20210114
The stromal microenvironment in the thymus is essential for generating a functional T cell repertoire. Thymic epithelial cells (TECs) are numerically and phenotypically one of the most prominent stromal cell types in the thymus, and have been recognized as one of most unusual cell types in the body by virtue of their unique functions in the course of the positive and negative selection of developing T cells. In addition to TECs, there are other stromal cell types of mesenchymal origin, such as f ...[more]