Unknown

Dataset Information

0

Reshaping preoperative treatment of pancreatic cancer in the era of precision medicine.


ABSTRACT: This review summarises the recent evidence on preoperative therapeutic strategies in pancreatic cancer and discusses the rationale for an imminent need for a personalised therapeutic approach in non-metastatic disease. The molecular diversity of pancreatic cancer and its influence on prognosis and treatment response, combined with the failure of 'all-comer' treatments to significantly impact on patient outcomes, requires a paradigm shift towards a genomic-driven approach. This is particularly important in the preoperative, potentially curable setting, where a personalised treatment allocation has the substantial potential to reduce pancreatic cancer mortality.

SUBMITTER: Casolino R 

PROVIDER: S-EPMC7840891 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC6901987 | biostudies-literature
| S-EPMC4505624 | biostudies-literature
| S-EPMC5404028 | biostudies-literature
| S-EPMC6245960 | biostudies-literature
| S-EPMC8194085 | biostudies-literature
| S-EPMC7794969 | biostudies-literature
| S-EPMC6290507 | biostudies-literature
| S-EPMC4828749 | biostudies-literature
| S-EPMC4541645 | biostudies-literature
| S-EPMC5119656 | biostudies-literature