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ABSTRACT: Objectives
Terrorist attacks and civilian mass-casualty events are frequent, and some countries have implemented tourniquet use for uncontrollable extremity bleeding in civilian settings. The aim of this study was to summarize current knowledge on the use of prehospital tourniquets to assess whether their use increases the survival rate in civilian patients with life-threatening hemorrhages from the extremities.Design
Systematic literature review in Medline (Ovid), Embase (Ovid), Cochrane Library, and Epistemonikos was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines. The search was performed in January 2019.Setting
All types of studies that examined use of tourniquets in a prehospital setting published after January 1, 2000 were included.Primary/secondary outcomes
The primary outcome was mortality with and without tourniquet, while adverse effects of tourniquet use were secondary outcomes.Results
Among 3,460 screened records, 55 studies were identified as relevant. The studies were highly heterogeneous with low quality of evidence. Most studies reported increased survival in the tourniquet group, but few had relevant comparators, and the survival benefit was difficult to estimate. Most studies reported a reduced need for blood transfusion, with few and mainly transient adverse effects from tourniquet use.Conclusion
Despite relatively low evidence, the studies consistently suggested that the use of commercial tourniquets in a civilian setting to control life-threatening extremity hemorrhage seemed to be associated with improved survival, reduced need for blood transfusion, and few and transient adverse effects.
SUBMITTER: Eilertsen KA
PROVIDER: S-EPMC7844612 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Eilertsen Kenneth A KA Winberg Morten M Jeppesen Elisabeth E Hval Gyri G Wisborg Torben T
Prehospital and disaster medicine 20201103 1
<h4>Objectives</h4>Terrorist attacks and civilian mass-casualty events are frequent, and some countries have implemented tourniquet use for uncontrollable extremity bleeding in civilian settings. The aim of this study was to summarize current knowledge on the use of prehospital tourniquets to assess whether their use increases the survival rate in civilian patients with life-threatening hemorrhages from the extremities.<h4>Design</h4>Systematic literature review in Medline (Ovid), Embase (Ovid), ...[more]