Multivariate Entropy Characterizes the Gene Expression and Protein-Protein Networks in Four Types of Cancer.
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ABSTRACT:
SUBMITTER: Juarez-Flores A
PROVIDER: S-EPMC7844632 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
Multivariate Entropy Characterizes the Gene Expression and Protein-Protein Networks in Four Types of Cancer.
Juarez-Flores Angel A José Marco V MV
Entropy (Basel, Switzerland) 20180228 3
There is an important urgency to detect cancer at early stages to treat it, to improve the patients' lifespans, and even to cure it. In this work, we determined the entropic contributions of genes in cancer networks. We detected sudden changes in entropy values in melanoma, hepatocellular carcinoma, pancreatic cancer, and squamous lung cell carcinoma associated to transitions from healthy controls to cancer. We also identified the most relevant genes involved in carcinogenic process of the four ...[more]
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