Ontology highlight
ABSTRACT:
SUBMITTER: Milani R
PROVIDER: S-EPMC7844640 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Milani Roberta R Brognara Eleonora E Fabbri Enrica E Finotti Alessia A Borgatti Monica M Lampronti Ilaria I Marzaro Giovanni G Chilin Adriana A Lee Kenneth Ka-Ho KK Kok Stanton Hon-Lung SH Chui Chung-Hin CH Gambari Roberto R
Oncology research 20170504 9
Glioblastoma multiforme (GBM), a malignant tumor of the central nervous system, has a high mortality rate. No curative treatment is presently available, and the most commonly used chemotherapeutic drug, the alkylating agent temozolomide (TMZ), is only able to increase life expectancy and is often associated with drug resistance. Therefore, an urgent need does exist for novel drugs aimed at treating gliomas. In the present study, we obtained three major results using corilagin: (a) demonstrated t ...[more]