Ontology highlight
ABSTRACT:
SUBMITTER: Kishikawa T
PROVIDER: S-EPMC7846180 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Kishikawa Toshihiro T Maeda Yuichi Y Nii Takuro T Arase Noriko N Hirata Jun J Suzuki Ken K Yamamoto Kenichi K Masuda Tatsuo T Ogawa Kotaro K Tsuji Shigeyoshi S Matsushita Masato M Matsuoka Hidetoshi H Yoshimura Maiko M Tsunoda Shinichiro S Ohshima Shiro S Narazaki Masashi M Ogata Atsushi A Saeki Yukihiko Y Inohara Hidenori H Kumanogoh Atsushi A Takeda Kiyoshi K Okada Yukinori Y
International immunology 20210101 2
Novel biomarkers of rheumatoid arthritis (RA), in addition to antibodies against cyclic citrullinated peptides, are required. Metabolome analysis is a promising approach to identify metabolite biomarkers for clinical diagnosis. We adopted a comprehensive non-targeted metabolomics approach combining capillary electrophoresis time-of-flight mass spectrometry (TOFMS) and liquid chromatography TOFMS. We constructed metabolomics profiling of 286 plasma samples of a Japanese population [92 RA patients ...[more]