Ontology highlight
ABSTRACT:
SUBMITTER: Werner JM
PROVIDER: S-EPMC7846805 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Communications biology 20210129 1
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural plate. Incomplete neural tube closure occurs frequently, yet underlying causes remain poorly understood. Developmental studies in amniotes and amphibians have identified hingepoint and neural fold formation as key morphogenetic events and hallmarks of primary neurulation, the disruption of which causes neural tube defects. In contrast, the mode of neurulation in teleosts h ...[more]