Ontology highlight
ABSTRACT:
SUBMITTER: Adolfi MC
PROVIDER: S-EPMC7848095 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Adolfi Mateus C MC Herpin Amaury A Martinez-Bengochea Anabel A Kneitz Susanne S Regensburger Martina M Grunwald David J DJ Schartl Manfred M
Frontiers in cell and developmental biology 20210118
Sex determination (SD) is a highly diverse and complex mechanism. In vertebrates, one of the first morphological differences between the sexes is the timing of initiation of the first meiosis, where its initiation occurs first in female and later in male. Thus, SD is intimately related to the responsiveness of the germ cells to undergo meiosis in a sex-specific manner. In some vertebrates, it has been reported that the timing for meiosis entry would be under control of retinoic acid (RA), throug ...[more]