Ontology highlight
ABSTRACT:
SUBMITTER: Izzi V
PROVIDER: S-EPMC7852311 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Izzi Valerio V Lakkala Juho J Devarajan Raman R Kääriäinen Anni A Koivunen Jarkko J Heljasvaara Ritva R Pihlajaniemi Taina T
Matrix biology plus 20190201
The microenvironment plays a central role in cancer, and neoplastic cells actively shape it to their needs by complex arrays of extracellular matrix (ECM) proteins, enzymes, cytokines and growth factors collectively referred to as the matrisome. Studies on the cancer matrisome have been performed for single or few neoplasms, but a more systematic analysis is still missing. Here we present a Pan-Cancer study of matrisome gene expression in 10,487 patients across 32 tumor types, supplemented with ...[more]