Ontology highlight
ABSTRACT:
SUBMITTER: Calabrese DR
PROVIDER: S-EPMC7852842 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Calabrese Daniel R DR Aminian Emily E Mallavia Benat B Liu Fengchun F Cleary Simon J SJ Aguilar Oscar A OA Wang Ping P Singer Jonathan P JP Hays Steven R SR Golden Jeffrey A JA Kukreja Jasleen J Dugger Daniel D Nakamura Mary M Lanier Lewis L LL Looney Mark R MR Greenland John R JR
The Journal of clinical investigation 20210201 3
Pulmonary ischemia-reperfusion injury (IRI) is a clinical syndrome of acute lung injury that occurs after lung transplantation or remote organ ischemia. IRI causes early mortality and has no effective therapies. While NK cells are innate lymphocytes capable of recognizing injured cells, their roles in acute lung injury are incompletely understood. Here, we demonstrated that NK cells were increased in frequency and cytotoxicity in 2 different IRI mouse models. We showed that NK cells trafficked t ...[more]