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Intrauterine Transmission of SARS-CoV-2.

ABSTRACT: We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissue. Placenta and umbilical cord blood tested positive for the virus by PCR, confirming transplacental transmission.

SUBMITTER: Stonoga ETS

PROVIDER: S-EPMC7853547 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Intrauterine Transmission of SARS-CoV-2.

Stonoga Emanuele T S ETS de Almeida Lanzoni Laura L Rebutini Patricia Zadorosnei PZ Permegiani de Oliveira André Luiz AL Chiste Jullie Anne JA Fugaça Cyllian Arias CA Prá Daniele M M DMM Percicote Ana Paula AP Rossoni Andrea A Nogueira Meri Bordignon MB de Noronha Lucia L Raboni Sonia Mara SM

Emerging infectious diseases 20201113 2

We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissue. Placenta and umbilical cord blood tested positive for the virus by PCR, confirming transplacental transmission. ...[more]

PMID: 33185524

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Intrauterine SARS-CoV-2 transmission

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