Ontology highlight
ABSTRACT:
SUBMITTER: Erlendsson S
PROVIDER: S-EPMC7854087 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Bio-protocol 20190920 18
Studying protein-protein and protein-lipid interactions in their native environment is highly desirable, yet, the heterogeneity and complexity of cellular systems limits the repertoire of experimental methods available. In cells, interactions are often taking place in confined microenvironments where factors such as avidity, hindered diffusion, reduced dimensionality, crowding <i>etc</i>. strongly influence the binding kinetics and therefore it can be problematic to equate binding affinities obt ...[more]