Short-term effect of non-surgical periodontal treatment on local and systemic cytokine levels: Role of hyperglycemia.

ABSTRACT:

Background

The effect of non-surgical periodontal treatment on oral and systemic inflammatory mediators in subjects with periodontitis and hyperglycemia remains largely unknown. Therefore, the aim of this clinical study was to compare the short-term effect of non-surgical periodontal treatment on serum, saliva and GCF inflammatory markers levels in GP subjects with or without hyperglycemia.

Methods

Sixty subjects divided into four groups of equal size were selected to participate: type 2 diabetics with generalized periodontitis (T2DM + GP), pre-diabetics with GP (PD + GP), normoglycemic subjects with GP (NG + GP), and healthy controls. GCF, serum, and saliva samples were obtained at baseline and 30 days after scaling and root planning (SRP) and the levels of interleukin-1β (

SUBMITTER: Rabelo MS 

PROVIDER: S-EPMC7855216 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature