Dataset Information

Influence of Magnetic Field Strength on Magnetic Resonance Imaging Radiomics Features in Brain Imaging, an In Vitro and In Vivo Study.

ABSTRACT:

Background

The development and clinical adoption of quantitative imaging biomarkers (radiomics) has established the need for the identification of parameters altering radiomics reproducibility. The aim of this study was to assess the impact of magnetic field strength on magnetic resonance imaging (MRI) radiomics features in neuroradiology clinical practice.

Methods

T1 3D SPGR sequence was acquired on two phantoms and 10 healthy volunteers with two clinical MR devices from the same manufacturer using two different magnetic fields (1.5 and 3T). Phantoms varied in terms of gadolinium concentrations and textural heterogeneity. 27 regions of interest were segmented (phantom: 21, volunteers: 6) using the LIFEX software. 34 features were analyzed.

Results

In the phantom dataset, 10 (67%) out of 15 radiomics features were significantly different when measured at 1.5T or 3T (student's t-test, p < 0.05). Gray levels resampling, and pixel size also influence part of texture features. These findings were validated in healthy volunteers.

Conclusions

According to daily used protocols for clinical examinations, radiomic features extracted on 1.5T should not be used interchangeably with 3T when evaluating texture features. Such confounding factor should be adjusted when adapting the results of a study to a different platform, or when designing a multicentric trial.

SUBMITTER: Ammari S

PROVIDER: S-EPMC7855708 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Publications

Influence of Magnetic Field Strength on Magnetic Resonance Imaging Radiomics Features in Brain Imaging, an <i>In Vitro</i> and <i>In Vivo</i> Study.

Ammari Samy S Pitre-Champagnat Stephanie S Dercle Laurent L Chouzenoux Emilie E Moalla Salma S Reuze Sylvain S Talbot Hugues H Mokoyoko Tite T Hadchiti Joya J Diffetocq Sebastien S Volk Andreas A El Haik Mickeal M Lakiss Sara S Balleyguier Corinne C Lassau Nathalie N Bidault Francois F

Frontiers in oncology 20210120

<h4>Background</h4>The development and clinical adoption of quantitative imaging biomarkers (radiomics) has established the need for the identification of parameters altering radiomics reproducibility. The aim of this study was to assess the impact of magnetic field strength on magnetic resonance imaging (MRI) radiomics features in neuroradiology clinical practice.<h4>Methods</h4>T1 3D SPGR sequence was acquired on two phantoms and 10 healthy volunteers with two clinical MR devices from the same ...[more]

PMID: 33552944

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