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Modeling multi-sensory feedback control of zebrafish in a flow.

ABSTRACT: Understanding how animals navigate complex environments is a fundamental challenge in biology and a source of inspiration for the design of autonomous systems in engineering. Animal orientation and navigation is a complex process that integrates multiple senses, whose function and contribution are yet to be fully clarified. Here, we propose a data-driven mathematical model of adult zebrafish engaging in counter-flow swimming, an innate behavior known as rheotaxis. Zebrafish locomotion in a two-dimensional fluid flow is described within the finite-dipole model, which consists of a pair of vortices separated by a constant distance. The strength of these vortices is adjusted in real time by the fish to afford orientation and navigation control, in response to of the multi-sensory input from vision, lateral line, and touch. Model parameters for the resulting stochastic differential equations are calibrated through a series of experiments, in which zebrafish swam in a water channel under different illumination conditions. The accuracy of the model is validated through the study of a series of measures of rheotactic behavior, contrasting results of real and in-silico experiments. Our results point at a critical role of hydromechanical feedback during rheotaxis, in the form of a gradient-following strategy.

SUBMITTER: Burbano-L DA

PROVIDER: S-EPMC7857640 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Modeling multi-sensory feedback control of zebrafish in a flow.

Burbano-L Daniel A DA Porfiri Maurizio M

PLoS computational biology 20210122 1

Understanding how animals navigate complex environments is a fundamental challenge in biology and a source of inspiration for the design of autonomous systems in engineering. Animal orientation and navigation is a complex process that integrates multiple senses, whose function and contribution are yet to be fully clarified. Here, we propose a data-driven mathematical model of adult zebrafish engaging in counter-flow swimming, an innate behavior known as rheotaxis. Zebrafish locomotion in a two-d ...[more]

PMID: 33481795

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Dataset Information

Modeling multi-sensory feedback control of zebrafish in a flow.

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Modeling multi-sensory feedback control of zebrafish in a flow.

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