Dataset Information

Clinical Characteristics and Predictors of Mortality in Minority Patients Hospitalized with COVID-19 Infection.

ABSTRACT:

Objectives

To identify the early mortality predictors in minority patients hospitalized with coronavirus disease 2019 (COVID-19).

Design

Demographics, presenting characteristics, admission laboratory data, ICU admission, and mortality data were collected from 200 consecutively hospitalized patients with COVID-19.

Results

The mean (SD) age was 58.9 (15.1) years, 121(60.5%) were men, 143 (71.5%) were African Americans, and 33 (16.5%) were Latino. Common presenting symptoms were cough 130 (65.0%), shortness of breath 129 (64.5%), and fever 121 (60.5%). One or more comorbid illness occurred in 171 (85.5%) and common comorbidities were hypertension (130 (65.2%)), diabetes (100 (50.0%)) and chronic kidney disease (60 (30.0%)). Of the 200 patients, 71 (35.5%) were treated in the ICU, 47 (24.2%) received mechanical ventilation, 45 (22.5%) died, and 155(77.5%) patients discharged home alive. The non-survivors were significantly older and had elevated markers of inflammation, coagulation, and acute organ damage on presentation. Age ??65 years (odds ratio (OR), 3.78; 95% CI, 1.74-8.22; P =?.001), lactate dehydrogenase level >?400 IU/L (OR, 9.1; 95% CI, 2.97-28.1; p ?20 mg/dl (OR, 5.56; 95%CI, 1.84-16.8; p ?2000 ng/ml (OR, 5.42; 95%CI, 1.63-17.9; p =?0.006), creatinine kinase >?1000 iu/l (OR, 3.57; 95% CI, 1.23 10.3; p =?0.019), procalcitonin >?2.5 ng/ml (OR, 4.21; 95% CI, 1.47-12.0; p =?0.007), D-dimer level >?3.0 ?g/ml (OR,10.9; 95% CI, 3.33-36.2; p =?< 0.001), creatinine >?2 mg/dl (OR, 4.5; 95% CI, 1.29-15.8; P =?0.018) at admission were associated independently with increases risk of in-hospital mortality.

Conclusion

Patients of advanced age that present with elevated biomarkers of inflammation, coagulation, and end-organ damage were at higher risk of mortality.

SUBMITTER: Muhammad R

PROVIDER: S-EPMC7861003 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Publications

Clinical Characteristics and Predictors of Mortality in Minority Patients Hospitalized with COVID-19 Infection.

Muhammad Rizwan R Ogunti Richard R Ahmad Basharat B Munawar Muhammad M Donaldson Sahai S Sumon Mahbubur M Kibreab Angesom A Thomas Alicia N AN Mehari Alem A

Journal of racial and ethnic health disparities 20210204 1

<h4>Objectives</h4>To identify the early mortality predictors in minority patients hospitalized with coronavirus disease 2019 (COVID-19).<h4>Design</h4>Demographics, presenting characteristics, admission laboratory data, ICU admission, and mortality data were collected from 200 consecutively hospitalized patients with COVID-19.<h4>Results</h4>The mean (SD) age was 58.9 (15.1) years, 121(60.5%) were men, 143 (71.5%) were African Americans, and 33 (16.5%) were Latino. Common presenting symptoms we ...[more]

PMID: 33538998

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Dataset Information

Clinical Characteristics and Predictors of Mortality in Minority Patients Hospitalized with COVID-19 Infection.

Objectives

Design

Results

Conclusion

Publications

Clinical Characteristics and Predictors of Mortality in Minority Patients Hospitalized with COVID-19 Infection.

Similar Datasets

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