Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure.
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ABSTRACT:
SUBMITTER: Teis A
PROVIDER: S-EPMC7862293 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
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Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure.
Teis Albert A Cediel G G Amigó N N Julve J J Aranyó J J Andrés-Cordón J J Puig-Jové C C Castelblanco E E Gual-Capllonch F F Ferrer-Sistach E E Vallejo N N Juncà G G López-Ayerbe J J De Antonio M M Domingo M M Santiago-Vacas E E Codina P P Mauricio D D Lupón J J Alonso Nuria N Bayes-Genis A A
Scientific reports 20210204 1
Evidence regarding any association of HDL-particle (HDL-P) derangements and HDL-cholesterol content with cardiovascular (CV) death in chronic heart failure (HF) is lacking. To investigate the prognostic value of HDL-P size (HDL-Sz) and the number of cholesterol molecules per HDL-P for CV death in HF patients. Outpatient chronic HF patients were enrolled. Baseline HDL-P number, subfractions and HDL-Sz were measured using 1H-NMR spectroscopy. The HDL-C/P ratio was calculated as HDL-cholesterol ove ...[more]
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