Dataset Information
Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level pooled analysis from the Disrupt CAD I and CAD II Studies.
Ontology highlight
ABSTRACT: Background
The aim of this study was to assess the safety and effectiveness of intravascular lithotripsy (IVL) in treating eccentric calcified coronary lesions.Methods
Between December 2015 and March 2019, 180 patients were enrolled in the Disrupt CAD I and CAD II studies across 19 sites in 10 countries. Patient-level data were pooled from these two studies (n?=?180), within which 47 eccentric lesions (26%) and 133 concentric lesions were identified.Results
Clinical success, defined as residual stenosis?ConclusionIn this first report from a pooled patient-level analysis of coronary IVL from the Disrupt CAD I and CAD II studies, IVL use was associated with consistent improvement in procedural and clinical outcomes in both eccentric and concentric calcified lesions.
SUBMITTER: Blachutzik F
PROVIDER: S-EPMC7862504 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level pooled analysis from the Disrupt CAD I and CAD II Studies.
Clinical research in cardiology : official journal of the German Cardiac Society 20200918 2
<h4>Background</h4>The aim of this study was to assess the safety and effectiveness of intravascular lithotripsy (IVL) in treating eccentric calcified coronary lesions.<h4>Methods</h4>Between December 2015 and March 2019, 180 patients were enrolled in the Disrupt CAD I and CAD II studies across 19 sites in 10 countries. Patient-level data were pooled from these two studies (n = 180), within which 47 eccentric lesions (26%) and 133 concentric lesions were identified.<h4>Results</h4>Clinical succe ...[more]