Ontology highlight
ABSTRACT: Objective
To estimate the prevalence of objectively confirmed olfactory and gustatory dysfunction in US adults reporting chronic rhinosinusitis (CRS) symptoms in a nationally representative database.Study design
Cross-sectional epidemiologic analysis.Setting
Data were analyzed from the smell and taste component of the 2013-2014 NHANES data set (National Health and Nutrition Examination Survey).Methods
Individuals reporting the presence of ?2 cardinal CRS symptoms (nasal blockage, sinus pain, discolored mucus, and dysosmia) were identified as patients with a potential diagnosis of CRS. Associations were examined between the presence of CRS symptoms and both self-reported and objectively measured smell and taste.Results
One-third (33%) of adults who have ?2 CRS symptoms report subjective olfactory impairment, though only 18% of these adults have quantifiable olfactory dysfunction on objective testing. Of these adults, 27% report subjective taste impairment, but just 17% have quantifiable gustatory dysfunction on objective testing. The presence of ?2 CRS symptoms was not significantly associated with objective olfactory or gustatory dysfunction, although the individual symptoms of subjective dysosmia and discolored mucus were associated with objectively confirmed olfactory dysfunction.Conclusion
The prevalence of objective olfactory and gustatory dysfunction was higher among adults reporting the presence of ?2 CRS symptoms, but the differences were not statistically significant. Specific sinonasal symptoms, including discolored mucus and subjective smell dysfunction, were significantly associated with objective smell impairment.
SUBMITTER: Kim JH
PROVIDER: S-EPMC7863166 | biostudies-literature | 2021 Jan-Mar
REPOSITORIES: biostudies-literature
OTO open 20210101 1
<h4>Objective</h4>To estimate the prevalence of objectively confirmed olfactory and gustatory dysfunction in US adults reporting chronic rhinosinusitis (CRS) symptoms in a nationally representative database.<h4>Study design</h4>Cross-sectional epidemiologic analysis.<h4>Setting</h4>Data were analyzed from the smell and taste component of the 2013-2014 NHANES data set (National Health and Nutrition Examination Survey).<h4>Methods</h4>Individuals reporting the presence of ≥2 cardinal CRS symptoms ...[more]