Ontology highlight
ABSTRACT:
SUBMITTER: Maciel NIG
PROVIDER: S-EPMC7863484 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Maciel Natália Ioseph Gladistone NIG Filiú-Braga Luma Dayane Carvalho LDC Neves Francisco Assis Rocha FAR Rego Eduardo Magalhaes EM Lucena-Araujo Antonio Roberto AR Saldanha-Araujo Felipe F
Biomarker research 20210204 1
Experimental evidence points to the role of Zinc fingers and homeoboxes protein 1 and 2 (ZHX1 and ZHX2) in the development and progression of several types of cancer, including hematological malignancies. Here, we determined whether the altered expression of ZHX1 and ZHX2 has clinical implications in patients with CLL. Interestingly, CLL patients with low expression ZHX1 and ZHX2 presented higher WBC counts. Importantly, our data showed that CLL patients with cytogenetic alterations presented re ...[more]