Ontology highlight
ABSTRACT:
SUBMITTER: Anderson MR
PROVIDER: S-EPMC7863776 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20190724 11
Frailty is a state of decreased physiologic reserve associated with poor outcomes before and after lung transplantation. Obesity, particularly central obesity characterized by excess proinflammatory visceral adipose tissue (VAT), is associated with incident frailty in middle-aged and older adults. The association between VAT and frailty in advanced lung disease, however, is unknown. In two, nonoverlapping multicenter cohorts of adults listed for lung transplantation, we measured VAT area on bioe ...[more]