Ontology highlight
ABSTRACT:
SUBMITTER: Ventz S
PROVIDER: S-EPMC7864990 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Ventz Steffen S Bacallado Sergio S Rahman Rifaquat R Tolaney Sara S Schoenfeld Jonathan D JD Alexander Brian M BM Trippa Lorenzo L
Nature communications 20210205 1
Most trials do not release interim summaries on efficacy and toxicity of the experimental treatments being tested, with this information only released to the public after the trial has ended. While early release of clinical trial data to physicians and patients can inform enrollment decision making, it may also affect key operating characteristics of the trial, statistical validity and trial duration. We investigate the public release of early efficacy and toxicity results, during ongoing clinic ...[more]