Ontology highlight
ABSTRACT:
SUBMITTER: Miller SM
PROVIDER: S-EPMC7865204 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Miller Shannon M SM Wang Tina T Liu David R DR
Nature protocols 20201116 12
Directed evolution, which applies the principles of Darwinian evolution to a laboratory setting, is a powerful strategy for generating biomolecules with diverse and tailored properties. This technique can be implemented in a highly efficient manner using continuous evolution, which enables the steps of directed evolution to proceed seamlessly over many successive generations with minimal researcher intervention. Phage-assisted continuous evolution (PACE) enables continuous directed evolution in ...[more]