Purinergic Regulation of Endothelial Barrier Function.
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ABSTRACT:
SUBMITTER: Aslam M
PROVIDER: S-EPMC7865261 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Purinergic Regulation of Endothelial Barrier Function.
Aslam Muhammad M Gündüz Dursun D Troidl Christian C Heger Jacqueline J Hamm Christian W CW Schulz Rainer R
International journal of molecular sciences 20210126 3
Increased vascular permeability is a hallmark of several cardiovascular anomalies, including ischaemia/reperfusion injury and inflammation. During both ischaemia/reperfusion and inflammation, massive amounts of various nucleotides, particularly adenosine 5'-triphosphate (ATP) and adenosine, are released that can induce a plethora of signalling pathways via activation of several purinergic receptors and may affect endothelial barrier properties. The nature of the effects on endothelial barrier fu ...[more]
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