Whole-Body MRI for the Detection of Recurrence in Melanoma Patients at High Risk of Relapse.

ABSTRACT: Introduction: No standard protocol for surveillance for melanoma patients is established. Whole-body magnetic resonance imaging (whole-body MRI) is a safe and sensitive technique that avoids exposure to X-rays and contrast agents. This prospective study explores the use of whole-body MRI for the early detection of recurrences. Material and Methods: Patients with American Joint Committee on Cancer Staging Manual (seventh edition; AJCC-7) stages IIIb/c or -IV melanoma who were disease-free following resection of macrometastases (cohort A), or obtained a durable complete response (CR) or partial response (PR) following systemic therapy (cohort B), were included. All patients underwent whole-body MRI, including T1, Short Tau Inversion Recovery, and diffusion-weighted imaging, every 4 months th

SUBMITTER: Jansen YJL 

PROVIDER: S-EPMC7865287 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature