Ontology highlight
ABSTRACT:
SUBMITTER: Al-Blewi F
PROVIDER: S-EPMC7866082 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Al-Blewi Fawzia F Shaikh Salma Akram SA Naqvi Arshi A Aljohani Faizah F Aouad Mohamed Reda MR Ihmaid Saleh S Rezki Nadjet N
International journal of molecular sciences 20210125 3
A library of novel imidazole-1,2,3-triazole hybrids were designed and synthesized based on the hybrid pharmacophore approach. Therefore, copper(I)catalyzed click reaction of thiopropargylated-imidazole 2 with several organoazides yielded two sets of imidazole-1,2,3-triazole hybrids carrying different un/functionalized alkyl/aryl side chains <b>4a-k</b> and <b>6a-e</b>. After full spectroscopic characterization using different spectral techniques (IR, <sup>1</sup>H, <sup>13</sup>C NMR) and elemen ...[more]