Ontology highlight
ABSTRACT:
SUBMITTER: Tarrago-Celada J
PROVIDER: S-EPMC7866204 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Tarragó-Celada Josep J Foguet Carles C Tarrado-Castellarnau Míriam M Marin Silvia S Hernández-Alias Xavier X Perarnau Jordi J Morrish Fionnuala F Hockenbery David D Gomis Roger R RR Ruppin Eytan E Yuneva Mariia M Atauri Pedro de P Cascante Marta M
Cancers 20210123 3
With most cancer-related deaths resulting from metastasis, the development of new therapeutic approaches against metastatic colorectal cancer (mCRC) is essential to increasing patient survival. The metabolic adaptations that support mCRC remain undefined and their elucidation is crucial to identify potential therapeutic targets. Here, we employed a strategy for the rational identification of targetable metabolic vulnerabilities. This strategy involved first a thorough metabolic characterisation ...[more]