Gut dysbiosis as a driver in alcohol-induced liver injury.
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ABSTRACT:
SUBMITTER: Fairfield B
PROVIDER: S-EPMC7868813 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
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Gut dysbiosis as a driver in alcohol-induced liver injury.
Fairfield Bradley B Schnabl Bernd B
JHEP reports : innovation in hepatology 20201210 2
Alcohol-related liver disease characterises a broad spectrum of hepatic diseases that result from heavy alcohol use, and include alcohol-related steatosis, steatohepatitis, fibrosis, cirrhosis, and alcoholic hepatitis. Amongst heavy drinkers, progression to more severe forms of alcohol-related liver disease is not universal, with only 20% developing cirrhosis and up to one-third developing alcoholic hepatitis. Non-alcohol-related triggers for severe disease are not well understood, but the intes ...[more]
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