Ontology highlight
ABSTRACT:
SUBMITTER: Ruigrok MJR
PROVIDER: S-EPMC7868939 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Ruigrok Mitchel J R MJR Frijlink Henderik W HW Melgert Barbro N BN Olinga Peter P Hinrichs Wouter L J WLJ
Molecular therapy. Methods & clinical development 20210120
Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which the lungs become irreversibly scarred, leading to declining lung function. As currently available drugs do not cure IPF, there remains a great medical need for more effective treatments. Perhaps this need could be addressed by gene therapies, which offer powerful and versatile ways to attenuate a wide range of processes involved in fibrosis. Despite the potential benefits of gene therapy, no one has reviewed the current state of k ...[more]