Cancer stem cells and macrophages: molecular connections and future perspectives against cancer.
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ABSTRACT:
SUBMITTER: Aramini B
PROVIDER: S-EPMC7869576 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Cancer stem cells and macrophages: molecular connections and future perspectives against cancer.
Aramini Beatrice B Masciale Valentina V Grisendi Giulia G Banchelli Federico F D'Amico Roberto R Maiorana Antonino A Morandi Uliano U Dominici Massimo M Haider Khawaja Husnain KH
Oncotarget 20210202 3
Cancer stem cells (CSCs) have been considered the key drivers of cancer initiation and progression due to their unlimited self-renewal capacity and their ability to induce tumor formation. Macrophages, particularly tumor-associated macrophages (TAMs), establish a tumor microenvironment to protect and induce CSCs development and dissemination. Many studies in the past decade have been performed to understand the molecular mediators of CSCs and TAMs, and several studies have elucidated the complex ...[more]
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