A review of methods for addressing components of interventions in meta-analysis.

ABSTRACT: Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex interventions with meta-analytical models. We summarized the methodology, highlighted new developments, and described the benefits, drawbacks, and potential challenges of each identified method. We expect meta-analytical methods focusing on components of several multicomponent interventions to become increasingly popular due to recently developed, easy-to-use, software tools that can be used to conduct the relevant analyses. The different meta-analytical methods are illustrated through two exampl

SUBMITTER: Petropoulou M 

PROVIDER: S-EPMC7870082 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature