Ontology highlight
ABSTRACT:
SUBMITTER: Gu YY
PROVIDER: S-EPMC7870688 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Gu Yue-Yu YY Lu Fu-Hua FH Huang Xiao-Ru XR Zhang Lei L Mao Wei W Yu Xue-Qing XQ Liu Xu-Sheng XS Lan Hui-Yao HY
Frontiers in pharmacology 20210126
Diabetic kidney disease (DKD) is the most common diabetic complication and is a leading cause of end-stage kidney disease. Increasing evidence shows that DKD is regulated not only by many classical signaling pathways but also by epigenetic mechanisms involving chromatin histone modifications, DNA methylation, and non-coding RNA (ncRNAs). In this review, we focus on our current understanding of the role and mechanisms of ncRNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in t ...[more]