Ontology highlight
ABSTRACT:
SUBMITTER: Jogalekar MP
PROVIDER: S-EPMC7871123 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Jogalekar Manasi P MP Veerabathini Anurag A Gangadaran Prakash P
Experimental biology and medicine (Maywood, N.J.) 20201109 2
Autophagy plays a crucial role in cellular development and differentiation as well as in the maintenance of homeostasis in healthy cells. Autophagy is well documented in neurodegenerative disorders, aging, and infectious diseases. However, recognizing its significance in cancer has always been challenging due to its tumor-promoting and suppressive attributes. Various modulators targeting key components of autophagy machinery directly or indirectly have been developed over the years, and have sho ...[more]