Dataset Information

Short-term effect of NO₂ on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.

ABSTRACT:

Objectives

As the largest organ of the human body, the skin is the major exposure route of NO₂. However, the evidence for a relationship between NO₂ exposure and dermatologic diseases (DMs) is limited. This time-series study was conducted to assess the short-term effect of nitrogen dioxide (NO₂) exposure on DMs outpatient visits in Xinxiang, China.

Methods

Daily recordings of NO₂ concentrations, meteorological data, and the outpatient visits data for DMs were collected in Xinxiang from January 1st, 2015, to December 31st, 2018. The analysis method used was based on the generalized additive model (GAM) with quasi-Poisson regression to investigate the relationship between NO₂ exposure and DMs outpatient visits. Several covariates, such as long-term trends, seasonality, and weather conditions were controlled.

Results

A total of 164,270 DMs outpatients were recorded. A 10 ?g/m³ increase in NO₂ concentrations during the period was associated with a 1.86% increase in DMs outpatient visits (95% confidence intervals [Cl]: 1.06-2.66%). The effect was stronger (around 6 times) in the cool seasons than in warmer seasons and younger patients (ConclusionsThe findings of this study indicate that short-term exposure to NO₂ increases the risk of DMs in Xinxiang, China, especially in the cool seasons. Policymakers should implement more stringent air quality standards to improve air quality.

SUBMITTER: Chao L

PROVIDER: S-EPMC7871127 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Short-term effect of NO<sub>2</sub> on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.

Chao Ling L Lu Mengxue M An Zhen Z Li Juan J Li Yuchun Y Zhao Qian Q Wang Yinbiao Y Liu Yue Y Wu Weidong W Song Jie J

Environmental geochemistry and health 20210209 9

<h4>Objectives</h4>As the largest organ of the human body, the skin is the major exposure route of NO<sub>2</sub>. However, the evidence for a relationship between NO<sub>2</sub> exposure and dermatologic diseases (DMs) is limited. This time-series study was conducted to assess the short-term effect of nitrogen dioxide (NO<sub>2</sub>) exposure on DMs outpatient visits in Xinxiang, China.<h4>Methods</h4>Daily recordings of NO<sub>2</sub> concentrations, meteorological data, and the outpatient vi ...[more]

PMID: 33559783

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Project description:Previous epidemiological studies have linked short-term exposure to particulate matter with outpatient visits for respiratory diseases. However, evidence on ultrafine particle (UFP) is still scarce in China. To investigate the association between short-term UFP exposure and outpatient visits for respiratory diseases as well as the corresponding lag patterns, information on outpatient visits for main respiratory diseases during January 1, 2017, to December 31, 2019 was collected from electronic medical records of two large tertiary hospitals in Shanghai, China. Generalized additive models employing a Quasi-Poisson distribution were employed to investigate the relationships between UFP and respiratory diseases. We computed the percentage change and its corresponding 95% confidence interval (CI) for outpatient visits related to respiratory diseases per interquartile range (IQR) increase in UFP concentrations. Based on a total of 1,034,394 hospital visits for respiratory diseases in Shanghai, China, we found that the strongest associations of total UFP with acute upper respiratory tract infection (AURTI), bronchitis, chronic obstructive pulmonary disease (COPD), and pneumonia occurred at lag 03, 03, 0, and 03 days, respectively. Each IQR increase in the total UFP concentrations was associated with increments of 9.02% (95% CI: 8.64-9.40%), 3.94% (95% CI: 2.84-5.06%), 4.10% (95% CI: 3.01-5.20%), and 10.15% (95% CI: 9.32-10.99%) for AURTI, bronchitis, COPD, and pneumonia, respectively. Almost linear concentration-response relationship curves without apparent thresholds were observed between total UFP and outpatient-department visits for four respiratory diseases. Stratified analyses illustrated significantly stronger associations of total UFP with AURTI, bronchitis, and pneumonia among female patients, while that with COPD was stronger among male patients. After adjustment of criteria air pollutants, these associations all remained robust. This time-series study indicates that short-term exposure to UFP was associated with increased risk of hospital visits for respiratory diseases, underscoring the importance of reducing ambient UFP concentrations for respiratory diseases control and prevention.

Dataset Information

Short-term effect of NO₂ on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.

Objectives

Methods

Results

Publications

Short-term effect of NO<sub>2</sub> on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.

Similar Datasets

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Dataset Information

Short-term effect of NO2 on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.

Objectives

Methods

Results

Publications

Short-term effect of NO<sub>2</sub> on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Short-term effect of NO₂ on outpatient visits for dermatologic diseases in Xinxiang, China: a time-series study.