Ontology highlight
ABSTRACT:
SUBMITTER: Hayashi S
PROVIDER: S-EPMC7873586 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Hayashi Shinya S Matsubara Tsukasa T Fukuda Koji K Maeda Toshihisa T Funahashi Keiko K Hashimoto Marowa M Kamenaga Tomoyuki T Takashima Yoshinori Y Kuroda Ryosuke R
Biomedical reports 20210129 3
Rheumatoid arthritis (RA) is a common chronic autoimmune disease leading to joint destruction. The aim of the present study was to identify the genomic factors predictive of susceptibility to joint destruction in patients with RA by performing a genome-wide association study of genetic variants, including single nucleotide polymorphisms (SNPs). The study sample included 228 patients with a diagnosis of RA in the past 5 years. Patients were classified into rapid (total Sharp score/years of RA, ≥5 ...[more]