Dataset Information
Phenomic profiling of a novel sibling species within the Scedosporium complex in Thailand.
Ontology highlight
ABSTRACT: Background
Scedosporium species are a group of pathogenic fungi, which can be found worldwide around high human-impacted areas. Infections of Scedosporium have been reported in several immunocompromised and immunocompetent patients with a high mortality rate. Recently, we have isolated and identified several Scedosporium strains during an environmental survey in Thailand.Results
We describe the isolate, TMMI-012, possibly a new species isolated from soils in the Chatuchak public park, Bangkok, Thailand. TMMI-012 is phylogenetically related to the Scedosporium genus and is a sibling to S. boydii but shows distinct morphological and pathological characteristics. It is fast growing and highly resistant to antifungal drugs and abiotic stresses. Pathological studies of in vitro and in vivo models confirm its high virulence and pathogenicity.Conclusion
TMMI-012 is considered a putative novel Scedosporium species. The high antifungal resistance of TMMI-012 compared with its sibling, Scedosporium species is likely related to its clinical impact on human health.
SUBMITTER: Kitisin T
PROVIDER: S-EPMC7874643 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
Phenomic profiling of a novel sibling species within the Scedosporium complex in Thailand.
BMC microbiology 20210209 1
<h4>Background</h4>Scedosporium species are a group of pathogenic fungi, which can be found worldwide around high human-impacted areas. Infections of Scedosporium have been reported in several immunocompromised and immunocompetent patients with a high mortality rate. Recently, we have isolated and identified several Scedosporium strains during an environmental survey in Thailand.<h4>Results</h4>We describe the isolate, TMMI-012, possibly a new species isolated from soils in the Chatuchak public ...[more]
