Integrated traditional Chinese medicine alleviates sciatica while regulating gene expression in peripheral blood.

ABSTRACT:

Background

Although integrated traditional Chinese medicine (TCM) has long been indicated to be effective in the treatment of sciatica and is widely used in the management of this condition, the mechanism by which integrated TCM alleviates sciatica has not yet been fully defined, and the effect of integrated TCM on gene expression in the peripheral blood of patients with sciatica is still unknown. We performed this study to investigate the effect of integrated TCM on peripheral blood gene expression in patients with sciatica and to explore new clues for studying the mechanism of integrated TCM in alleviating sciatica.

Methods

We used a microarray to identify differentially expressed genes (DEGs) in the peripheral blood of patients with sciatica and healthy controls (DEGs-bas

SUBMITTER: Wang Y 

PROVIDER: S-EPMC7877113 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature