Ontology highlight
ABSTRACT:
SUBMITTER: Ahangari N
PROVIDER: S-EPMC7877934 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Ahangari Najmeh N Doosti Mohammad M Ghayour Mobarhan Majid M Sahebkar Amirhossein A Ferns Gordon A GA Pasdar Alireza A
Annals of medicine 20200824 8
Statins are the first-line choice in Lipid-lowering therapy to reduce cardiovascular risk. In a continuous attempt to optimise treatment success, there is a need for additional research on genes and related molecular pathways that can determine the efficacy and toxicity of lipid-lowering drugs. Several variations within genes associated with lipid metabolism, including those involved in uptake, distribution and metabolism of statins have been reported. The purpose of this study was to evaluate t ...[more]