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ABSTRACT:
SUBMITTER: Gaudreault J
PROVIDER: S-EPMC7878517 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Gaudreault Jimmy J Liberelle Benoît B Durocher Yves Y Henry Olivier O De Crescenzo Gregory G
Scientific reports 20210211 1
Surface plasmon resonance-based biosensors have been extensively applied to the characterization of the binding kinetics between purified (bio)molecules, thanks to robust data analysis techniques. However, data analysis for solutions containing multiple interactants is still at its infancy. We here present two algorithms for (1) the reliable and accurate determination of the kinetic parameters of N interactants present at different ratios in N mixtures and (2) the estimation of the ratios of eac ...[more]