Ontology highlight
ABSTRACT:
SUBMITTER: Weglarz-Tomczak E
PROVIDER: S-EPMC7878891 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Scientific reports 20210211 1
An efficient treatment against a COVID-19 disease, caused by the novel coronavirus SARS-CoV-2 (CoV2), remains a challenge. The papain-like protease (PL<sup>pro</sup>) from the human coronavirus is a protease that plays a critical role in virus replication. Moreover, CoV2 uses this enzyme to modulate the host's immune system to its own benefit. Therefore, it represents a highly promising target for the development of antiviral drugs. We used Approximate Bayesian Computation tools, molecular model ...[more]