Ontology highlight
ABSTRACT:
SUBMITTER: Chang Y
PROVIDER: S-EPMC7879482 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Chang Yeonji Y Lim Gyubum G Huh Won-Ki WK
The Journal of cell biology 20210401 4
The target of rapamycin complex 1 (TORC1) is mainly localized to the vacuolar membrane and regulates eukaryotic cell growth in response to nutrient availability. To obtain deeper insights into the functional roles of TORC1, we performed a genome-wide analysis of the TORC1 interactome in yeast using the bimolecular fluorescence complementation (BiFC) assay. We found that while most of the BiFC signals are observed at the vacuolar membrane, a fraction of them are detected at cytoplasmic messenger ...[more]