Ontology highlight
ABSTRACT:
SUBMITTER: Cribaro GP
PROVIDER: S-EPMC7879533 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Cribaro George P GP Saavedra-López Elena E Romarate Leire L Mitxitorena Izaskun I Díaz Laura R LR Casanova Paola V PV Roig-Martínez Meritxell M Gallego José M JM Perez-Vallés Ana A Barcia Carlos C
Acta neuropathologica communications 20210212 1
The cellular complexity of glioblastoma microenvironments is still poorly understood. In-depth, cell-resolution tissue analyses of human material are rare but highly necessary to understand the biology of this deadly tumor. Here we present a unique 3D visualization revealing the cellular composition of human GBM in detail and considering its critical association with the neo-vascular niche. Our images show a complex vascular map of human 3D biopsies with increased vascular heterogeneity and alte ...[more]