Ontology highlight
ABSTRACT:
SUBMITTER: Yao Q
PROVIDER: S-EPMC7880343 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Aging 20201219 2
Systemic sclerosis (SSc) is a prototypic fibrotic disease characterized by localized or diffuse skin thickening and fibrosis. Tissue fibrosis is driven by myofibroblasts, and factors affecting myofibroblast activation may also be involved in the development of SSc. In this study, we examined molecular mechanisms underlying SSc by focusing on myofibroblast activation processes. Bioinformatics analysis conducted to identify differentially expressed miRNAs (DEMs) and genes (DEGs) revealed that micr ...[more]