MRI evaluation of normal tissue deformation and breathing motion under an abdominal compression device.

ABSTRACT:

Purpose

Abdominal compression can minimize breathing motion in stereotactic radiotherapy, though it may impact the positioning of dose-limiting normal tissues. This study quantified the reproducibility of abdominal normal tissues and respiratory motion with the use of an abdominal compression device using MR imaging.

Methods

Twenty healthy volunteers had repeat MR over 3 days under an abdominal compression plate device. Normal tissues were delineated on daily axial T2-weighted MR and compared on days 2 and 3 relative to day 1, after adjusting for baseline shifts relative to bony anatomy. Inter-fraction organ deformation was computed using deformable registration of axial T2 images. Deformation > 5 mm was assumed to be clinically relevant. Inter-fraction respiratory amplitude

SUBMITTER: Lee M 

PROVIDER: S-EPMC7882116 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature