Mosaic Evolution of the Phosphopantothenate Biosynthesis Pathway in Bacteria and Archaea.
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ABSTRACT:
SUBMITTER: Thomes L
PROVIDER: S-EPMC7883664 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
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Mosaic Evolution of the Phosphopantothenate Biosynthesis Pathway in Bacteria and Archaea.
Genome biology and evolution 20210201 2
Phosphopantothenate is a precursor to synthesis of coenzyme A, a molecule essential to many metabolic pathways. Organisms of the archaeal phyla were shown to utilize a different phosphopantothenate biosynthetic pathway from the eukaryotic and bacterial one. In this study, we report that symbiotic bacteria from the group Candidatus poribacteria present enzymes of the archaeal pathway, namely pantoate kinase and phosphopantothenate synthetase, mirroring what was demonstrated for Picrophilus torrid ...[more]
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